What is EIM?
Electrical impedance myography, or EIM is a non-invasive technique for the assessment of muscle health that is based on the measurement of the electrical impedance characteristics of individual muscles or groups of muscles.
mScan™
A convenient. easy-to-use muscle health assessment system that monitors and displays bioimpedance.
*IRB-approved. Pending FDA approval.
Clinical practice or clinical trails
No need to understand the physiological basis of the measurements
Machine learning
Machine learning-based algorithms for optimized performance
Normalized data
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impedance measures
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- mScan measures impedance characteristics across multiple frequencies and at multiple angles relative to the major muscle fiber direction.
- Current (blue) and voltage (yellow) electrodes are placed on a specific location over a muscle. A weak electrical current is passed through the tissue across a wide range of frequencies through the current electrodes.
- Alterations in the health of the muscle are reflected in the measured voltages.
The Three Measures of EIM
Resistance
Resistance of an object is a measure of its opposition to the flow of electric current. Its reciprocal quantity is electrical conductance, measuring the ease with which an electric current passes. Increased tissue resistance causes higher amplitude voltage.
Reactance
Reactance is the opposition presented to alternating current by inductance or capacitance. In tissue, however, there is no inductive elements, and thus we only care about capacitance which is due to the presence of cell membranes which at as mini-capacitors. Reduced tissue capacitance in disease causes a change in measured reactance.
Phase
The phase serves as a convenient combination of resistance and reactance, and it is less impacted by muscle size or shape. Phase represents the time-shift that a sinusoid undergoes when passing through the muscle.